Welcome to NaviFUS

NaviFUS is a Biotech company dedicated to providing novel platform solutions for crossing the blood-brain-barrier (BBB) for enhanced oncology drug delivery.

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About Us


The Team

Team People

Jen Chen, Ph.D.


Dr.Chen has over 30 years of new drug hunting/ development experience, he managed a fully integrated biopharmaceutical company (Genovate Biotechnology)engaged in developing new drugs, manufacturing high-quality pharmaceuticals, selling and marketing products.

Team People

Arthur Lung, Ph.D.

Chief Executive Officer

Dr. Lung had over 25 years of medical device product development/ marketing experience and devoted into 24 product-launching works during his career in United Orthopedic and Medtronic-Weigao. He also has experience in entrepreneurship for the health industry.

Team People

Hao-Li Liu, Ph.D.

Founder & Chief Technology Officer

Dr. Liu is currently the Distinguished Professor of Department of Electrical Engineering, Chang-Gung University. He has published over 100 SCI papers and over 30 patents filed in areas of biomedical use of therapeutic ultrasound. He also was the primary designer for NaviFUS system.

NaviFUS History


NaviFUS Corp. was founded in 2015 with novel ultrasound technology based on years of essential academic research development by Dr. Hao-Li Liu at the Department of Electrical Engineering of Chang Gung University in Taiwan. The company successfully secured Series A1 and A2 funding for total USD 13M from Taiwan’s Venture Capital & pharmaceutical industry separately in 2016 and 2018. The company actively conducted clinical studies for the brain tumor and epilepsy in Taiwan. In 2018, the company also co-invested with Genovate Biotechnology Co., Ltd. for setting up a subsidiary company in Austria and aimed at the corporation for clinical studies in the therapy area except for brain tumor (e.g., Alzheimer's disease).

Major Milestones

NaviFUS system got a phase 1 clinical trial approval for epilepsy in Taiwan
Accepted as “Fast Track Case” from Center of Drug Evaluation consultation
The first trial for NaviFUS system in rGBM recruited its 1st patient.
NaviFUS Corp. closed Series A2 funding of $7M USD.
NaviFUS system got an IDE qualification and a phase 1 clinical trial approval for rGBM in Taiwan.
NaviFUS Corp. closed Series A1 funding of $6M USD from Taiwan’s Venture Capital & pharmaceutical industry.
Accepted as “Actively-Guided Case” from Taiwan Food & Drug Administration Consultation.
U.S. FDA Pre-submission Meeting held.
NaviFUS Corp. was founded in Taiwan with funding from private investors.
Chang Gung University R&D supported by major government funded projects.

NaviFUS Product



Company News

Blog Post

The Navifus System has been getting a clinical trial approval for Drug-Resistant Epilepsy in Taiwan

20th Feb, 2019

NaviFUS announced that their focus ultrasound system (NaviFUS system) had gotten the clinical trial approval from TFDA for the treatment of drug-resistant epilepsy(DRE). The primary goal of this trial is validation the safety of NaviFUS system using in DRE. Subjects recruiting will start in April …

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Blog Post

Navifus has been updating the progression of current trial for rGBM patients

15th Nov, 2018

Taiwan-based focused ultrasound manufacturer NaviFUS recently announced the start of its first clinical trial for glioblastoma. To date, three patients have been treated. Researchers at Chang Gung Memorial Hospital are investigating focused ultrasound to induce opening of the blood-brain barrier (BBB) in patients with glioblastoma using optically guided, neuronavigational technology…

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Blog Post

Navifus disclosed the early safety data for rGBM patients in 6th ISFU, 2018, USA

24th Oct, 2018

The 6th International Symposium on Focused Ultrasound (ISFU) was held in Reston, Virginia, demonstrating the field's immense progress and the groundbreaking technology's potential to transform medical therapy worldwide. More than 450 clinicians, scientists, government employees and industry representatives from around the globe gathered October 21–25 to hear 250 presentations on the latest research, including key clinical milestones for neurological indications such as brain tumors, epilepsy, Parkinson's disease, Alzheimer's disease, OCD, and depression.
Chief Executive Officer Dr. Lung participate in this symposium and disclosed the initial safety result of FIH trial about " FUS Open BBB" in rGBM patient at Linkou Chang Gung Memorial Hospital (Taiwan)…

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Blog Post

The Navifus System has been getting an IDE qualification and a FIH clinical trial for rGBM patients

29th Jan, 2018

The NaviFus Focus Ultrasound System has been getting investigational Device Exemption (IDE) qualification and accepted to execute FIH clinical trial in Q1 for rGBM patients by TFDA Consulting.
It’s a pioneer of brain tumor therapy by using FUS opening BBB temporally in Taiwan’s clinical study. In addition to brain tumors, it is also actively expanding the use of this technology in other central nervous diseases, such as Alzheimer's disease, epilepsy and so on…

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Blog Post

The prototype of NaviFUS System has debuted in the “FUTURE TECH, 2017” Exhibition in Taiwan

2nd Jan, 2018

"Future Tech, 2017" in Taiwan assembles 109 breakthroughs and industrial applications of forward-looking technology’s research achievements from72 study institutes to participate such as MOST、Science Park、NARLABS、NIH, NSRRC, NCDR… etc. The area including biotechnology and new drugs, Medical materials, electronics and optoelectronics, metal chemicals and innovative materials.
The prototype of Navifus System is also debuted in the exhibition, the system can guide the specific frequency ultrasound to the appropriate position of the temporary opening blood-brain barrier (BBB) and enhance the treatment by helping the drug release.

Blog Post

NaviFUS executives visit FUS Foundation

14th Feb, 2017

Executives from NaviFUS, a new focused ultrasound company in Taiwan, visited the Foundation to share information on the status of ...

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Blog Post

The NaviFUS System received winner of 12th National Innovation Award


Estimation of 98% of current therapeutic agents in the blood stream can not reach brain tumor tissues due to human body's blood-brain-barrier, causing poor cancer treatment...

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Blog Post

The NaviFUS system was reported by Fortune Magazine

13th Jun, 2014

By concentrating acoustic energy into the body, we can heat and destroy tumors caused by cancerous cells...

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Blog Post

The NaviFUS system was reported by IEEE Spectrum

22nd May, 2014

Window In The Brain: A 256-channel ultrasound array has been tested on a pig. The array could electronically steer ultrasound energy to open ...

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Visit Us

Address 12F., No. 246, Sec. 3, Chengde Rd., Datong Dist., Taipei City 103, Taiwan

Call Us (Tel) +886-2-2586-0560
(Fax) +886-2-2537-6373

Email info@navifus.com

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